modRNA, mismarketed mrna
First posted online: 6 April 2022
The UK government and the NHS have mismarketed the modRNA COVID-19 "vaccines" by Pfizer and Moderna. The MHRA betrayed us with their Regulation 174 temporary authorisations. The CDC continue to falsely claim, "our cells break down mRNA and get rid of it within a few days."
The MHRA’s own advice is that live attenuated vaccines (LAVs) should not be administered to the clinically immunosuppressed, precisely because by replicating too many times, the vaccine itself could overwhelm the host immune system, causing severe disease and even death.
Genetic COVID-19 drugs aren’t loaded with natural mRNA, but synthetic modRNA to increase translational efficiency: swapping uridine for N1-methylpseudouridine, encoding GC-rich codon-optimised sequences, complete with 5' and 3' modifications in the untranslated region.
With all these hacks just to stabilise the fragile modRNA molecules encapsulated in lipid (fatty) capsules, we don’t know exactly how quickly the modRNA breaks down, but we know it isn’t quick. Lots of spike protein is produced at the ribosomes and for a long time.
Spike protein was found in 96% of vaccinees' plasma within 2 days of Dose 1, a level akin to an acute COVID-19 case. Spike is also expressed on exosomes in the blood. This may explain shedding, a phenomenon monitored in Pfizer’s trial, which the FDA previously described.
It is now known that both the lipid nanoparticles (LNPs) and spike protein persist in human lymph nodes for up to 8 weeks. Pfizer’s rat model study showed the positively charged LNPs are delivered to organs across the body. Spike protein was also synthesised in mice liver.
These drugs do not provide safe immunological training but deliver toxic foreign protein to organs. This may further induce inflammatory responses. The healthy and fit, the immunocompetent, seem to fare poorly! VAERS data shows teenage boys worst afflicted by myocarditis.
So, is it fair to class modRNA drugs the same as traditional inactivated vaccines? These drugs have been specifically crafted to deliver heavily fortified genetic code, encapsulated in a lipid construct, further shielded by a positive charge to slip through the endosomes!
modRNA is lab-modified to increase efficiency
The CDC falsely claim vaccinal "mRNA" swiftly breaks down
MHRA 2016 update on LAVs
Röltgen et al. on modRNA/spike persistence
Bansal et al. on exosomes
Pfizer trial protocol
FDA gene therapy guide https://www.fda.gov/files/vaccines%2C%20blood%20%26%20biologics/published/Design-and-Analysis-of-Shedding-Studies-for-Virus-or-Bacteria-Based-Gene-Therapy-and-Oncolytic-Products--Guidance-for-Industry.pdf
Pfizer biodistribution studies https://www.pmda.go.jp/drugs/2021/P20210212001/672212000_30300AMX00231_I100_1.pdf
Oster et al. on myocarditis