is spike a neurotoxic venom?

First posted online: 23 April 2022

Was the SARS-CoV-2 spike protein crafted as a nerve agent? Are full-spike "vaccines" a cruel means to mass deploy a neurotoxin, spike? Back in 2020, researchers identified toxin-like amino acid sequences on the spike protein, similar to snake venom neurotoxin homolog NL1.

Peptides (amino acid sequences) identified from the plasma, urine and faeces of COVID-19 patients suggest a near perfect match with toxic components of venoms expressed by animals that include marine cone snails, kraits and cobras.

Snake venom neurotoxins bind with nicotinic acetylcholine receptors (nAChRs), expressed abundantly by nerve cells (neurons) throughout the central and peripheral nervous systems. Could S-to-nAChRs interactions help to explain some vaccine-induced neurological side effects?

Novel modRNA COVID-19 "vaccines" ensure high levels of spike protein circulate in the bloodstream. Spike can cross the blood-brain barrier, risking delicate neural networks. Besides this, 1% of Pfizer's LNPs concentrated in the (innervated) spleen in the murine model.

Both snake venom and spike protein interact with platelets, changing their shape and inducing platelet secretions including α granulations and pro-inflammatory serotonin. These activated platelets can lead to blood disorders: thrombocytopenia and coagulopathy.

In August 2020, Chinese pharmacologists even suggested cobra venom (cobrotoxin) as a potential therapeutic against COVID-19. Its action as an anti-inflammatory and antiviral agent may mainly be due to its broad ability to bind to various subtypes of nAChRs.

Whilst ACE2 is widely accepted to be the main target receptor for viral replication, therapeutically blocking nAChRs may help to prevent the most severe COVID-19 symptoms. It alone could potentially stop the envenomation!

Venom-like peptides may suggest it is a genetically engineered bioweapon, the culmination of years of research to develop a toxic payload. There is still another clue to its unnatural origin, distinguishing the spike protein from RatG13, its closest wild bat coronavirus.

The spike protein contains a novel polybasic furin cleavage site with a 4 amino acid insert, PRRA, integral to ACE2-dependent infection of epithelial cells. Furin cleavage is a requisite for the membrane-host cell fusion reaction prior to viral replication.

We shouldn’t be so focused on inhibiting viral replication as to miss the importance of deploying therapeutics to block the nACh receptor to prevent envenomation. Most vitally, nobody should ever receive a full-spike "vaccine", likely an envenomated-spike delivery vector!

Amino acid positions 375-390 from S1 subunit of wild-type spike protein shares similarities with positions 41-72 of snake venom neurotoxin NL1

Snake venom and SARS-CoV-2 share mechanisms of action